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In vitro studies, such as those that produce a stretch-induced model of injury to murine hippocampal cells, demonstrate that repeated insults produce more pronounced damage to both neurons and glia than single insults (Slemmer and Weber, 2005

Changes in GRK2 Expression Level Impact Endothelial Cell Activity The AKT pathway is implicated in vascular endothelial growth factor (VEGF)-A-dependent EC function, including cell survival, proliferation, and generation of nitric oxide, via the VEGF receptor-2/PI3K/AKT-PKB axis (40, 41)

doi: 10.1161/HYPERTENSIONAHA.118.12389 138 KellyB.PearceE

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